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Noromectin Vet.

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Document: Noromectin vet. solution for injection ENG PL change

PACKAGE LEAFLET FOR:

Noromectin vet. 10 mg/ml, solution for injection

ivermectin



NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER AND OF THE MANUFACTURING AUTHORISATION HOLDER RESPONSIBLE FOR BATCH RELEASE, IF DIFFERENT


Norbrook Laboratories Limited

Station Works

Camlough Road

Newry

Co. Down

BT35 6JP

Northern Ireland


NAME OF THE VETERINARY MEDICINAL PRODUCT


Noromectin vet. 10 mg/ml, solution for injection


STATEMENT OF THE ACTIVE SUBSTANCE(S) AND OTHER INGREDIENTS

Active substance(s):

1 ml contains:

Ivermectin 10 mg


Excipient(s):

Glycerolformal 0,4 ml

(Glycerol formal contains as stabilisers:

Thiodipropionic acid, N-propyl gallate,

Disodium edetate)

Macrogol 200 ad 1,0 ml


INDICATION(S)


Noromectin vet. is indicated for treatment of the following parasites by cattle, pig and reindeer:


Cattle

Gastro-intestinal roundworms (adult and fourth stage larvae, L4):

Ostertagia ostertagi (including inhibited L4)

Ostertagia lyrata

Haemonchus placei

Trichostrongylus axei

Trichostrongylus colubriformis (L4)

Cooperia oncophora

Cooperia punctata

Cooperia pectinata

Nematodirus spatiger (adult)

Oesophagostomum radiatum


Lungworms (adult and fourth stage larvae, L4):

Dictyocaulus viviparus


Warbles (larval stages)

Hypoderma bovis

Hypoderma lineatum


Mange Mites

Sarcoptes scabiei var. bovis

Psoroptes bovis


Lice

Linognathus vituli

Haematopinus eurysternus


Pig


Gastro-intestinal roundworms (adult and fourth stage larvae, L4):

Ascaris suum

Hyostrongylus rubidus

Oesophagostomum spp.

Strongyloides ransomi (adult)


Lungworms

Metastrongylus spp. (adult)


Mange Mites

Sarcoptes scabiei var. suis


Lice

Haematopinus suis


Reindeer


Larval stages of Oedemagena tarandi


CONTRAINDICATIONS


Should not be injected in animals with known hypersensitivity to ivermectins.


ADVERSE REACTIONS


Local reaction (discomfort and swelling) has been observed.


If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.


TARGET SPECIES


Cattle, pig and reindeer.


DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION


Cattle and reindeer: 1 ml Noromectin vet. per 50 kg body weight, corresponding to 0,2 mg ivermectin per kg body weight injected subcutaneously.

Pigs: 1 ml Noromectin vet. per 33 kg body weight, corresponding to 0,3 mg ivermectin per kg body weight injected subcutaneously.


ADVICE ON CORRECT ADMINISTRATION



WITHDRAWAL PERIOD


Meat and offal: Cattle 49 days and pig and reindeer 28 days


Lactating dairy cattle must not be injected. Dry cows and heifers must not be injected later than 60 days prior to calving.


SPECIAL STORAGE PRECAUTIONS


Keep out of the reach and sight of children


Do not store above 25°C.


Keep the container in the outer carton in order to protect from light.


Do not use after the expiry date stated on the carton.

Shelf life after first opening: 28 days


SPECIAL WARNINGS


Neonatal pigs are sensitive for overdosing of ivermectin, probably because of a higher permeability of the blood-brain-barrier.

Piglets <5 days should not be injected.


In non-target species, ivermectins/milbemycins can be less well tolerated. (Cases of intolerance with fatal consequences have been reported in dogs, particularly collies, Old English Sheepdogs and related breeds and turtles).


Pregnancy and lactation

Noromectin vet. can be administered to beef cows and pigs at any stage of pregnancy or lactation. Noromectin vet. must not be administered to lactating dairy cattle, dry cows or heifers later than 60 days prior to calving, when milk is intended for human consumption.


SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE MATERIALS, IF ANY


Free ivermectin is extremely toxic to aquatic life. Residual contents should be returned to the Pharmacies for destruction.


DATE ON WHICH THE PACKAGE LEAFLET WAS LAST APPROVED


2009-10-01


OTHER INFORMATION

Pack sizes: 50 ml, 100 ml, 250 ml, 6x250 ml, 500 ml.

Not all pack sizes may be marketed